SS-31 (Elamipretide) Research Peptide

Mitochondria-Targeted Tetrapeptide — Cardiolipin-binding peptide for bioenergetics, oxidative stress, and mitochondrial function research

✓ 99%+ Purity HPLC Verified ✓ COA Included ✓ Fast USA Shipping ✓ Mitochondria-Targeted ✓ Research Grade
From $49.99
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Choose Your Research Supply

SS-31 5mg Vial

Entry research supply — ideal for initial mitochondrial membrane and cardiolipin binding studies

$49.99
Order 5mg

SS-31 10mg Vial

Extended supply for longitudinal mitochondrial bioenergetics and ROS research

$84.99
Order 10mg

SS-31 Research Pack (2×10mg)

Comprehensive supply for multi-protocol mitochondrial function research programs

$129.99
Order 2-Pack

Why Researchers Choose AscendLabz

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99%+ Purity Guaranteed

Every SS-31 batch undergoes HPLC analysis. Certificate of Analysis confirming purity and identity provided.

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Competitive Research Pricing

Premium elamipretide from $49.99 — best-value mitochondria-targeted peptide in the USA.

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Fast Discrete Shipping

Ships within 24–48 hours. Discreet packaging with tracked USA delivery on every order.

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Certificate of Analysis

Full COA with peptide identity, purity confirmation, and batch number included with every shipment.

SS-31 Specifications

Peptide NameSS-31 / Elamipretide / MTP-131
SequenceD-Arg-Dmt-Lys-Phe-NH2
Molecular FormulaC₃₂H₄₉N₉O₅
Molecular Weight639.80 g/mol
TargetCardiolipin (inner mitochondrial membrane)
Purity≥99% (HPLC verified)
FormLyophilized powder
Storage-20°C (long-term), 2–8°C (short-term)
Available Sizes5mg, 10mg

Frequently Asked Questions

What is SS-31 (Elamipretide) used for in research?

SS-31 is a mitochondria-targeted tetrapeptide that selectively binds cardiolipin in the inner mitochondrial membrane. Research focuses on its effects on mitochondrial cristae structure, electron transport chain efficiency, ATP production, and reactive oxygen species (ROS) reduction in cell and animal models.

How does SS-31 target mitochondria specifically?

SS-31 contains alternating aromatic and cationic residues that create an amphipathic structure. This allows cell-permeable uptake and selective concentration at the inner mitochondrial membrane through electrostatic interactions with cardiolipin, without requiring a mitochondrial targeting sequence.

Does AscendLabz provide a COA for SS-31?

Yes — every SS-31 order includes a Certificate of Analysis confirming ≥99% purity via HPLC, peptide sequence identity, and batch traceability for complete research documentation.

Research Background

SS-31 (Elamipretide) is a aromatic-cationic tetrapeptide that selectively binds cardiolipin on the inner mitochondrial membrane studied as part of the mitochondrial cardiolipin peptide category. It is investigated in pre-clinical and in-vitro research models for its activity on cardiolipin stabilization, electron transport chain integrity, and mitochondrial ROS pathways studied in vitro. The compound is supplied as a lyophilized powder of ≥99% HPLC-verified purity and is intended exclusively for laboratory research use under qualified scientific supervision.

AscendLabz SS-31 (Elamipretide) is sourced from cGMP-aligned synthesis facilities and validated for identity, purity, and counter-ion content prior to release. Each lot is independently tested by HPLC, and a Certificate of Analysis (COA) detailing peak area, retention time, and batch number is provided with every order. This level of documentation is intended to support reproducible research and clear chain-of-custody record-keeping in academic and independent laboratory environments.

For research workflows, SS-31 (Elamipretide) is most commonly characterized in cell-culture and isolated-tissue models where investigators examine cardiolipin binding and mitochondrial membrane stabilization alongside complementary compounds in the mitochondrial-targeted research peptides class. Reference standards and dose-response controls should be established by each laboratory prior to experimental use, and all material should be handled by trained personnel using appropriate personal protective equipment.

Storage, Handling & Reconstitution

Storage: Lyophilized SS-31 is stable at -20°C protected from light. Reconstituted peptide should be refrigerated at 2-8°C and used within 14 days. Lyophilized peptides should be kept in original sealed packaging until use to prevent moisture uptake.

Reconstitution: Bring the lyophilized vial to room temperature before opening. Reconstitute with bacteriostatic water by injecting solvent down the inner wall of the vial; do not direct the stream onto the lyophilized cake. Gently swirl — do not vortex or shake — until fully dissolved. Allow 5-10 minutes for complete solvation.

Handling: Use sterile technique throughout. Wipe vial septa with isopropyl alcohol before each draw. Document reconstitution date, solvent volume, and resulting concentration on the vial label for traceability.

Extended Research FAQ

How is SS-31 (Elamipretide) verified for purity?

Every batch of SS-31 (Elamipretide) is analyzed by reverse-phase HPLC and confirmed to be ≥99% pure. Mass spectrometry confirms molecular identity, and counter-ion / residual-solvent panels are performed where applicable. The full Certificate of Analysis ships with each order and is also archived by lot number.

Is SS-31 (Elamipretide) approved for human use?

No. SS-31 (Elamipretide) is supplied strictly for in-vitro laboratory research and is not approved by the FDA, EMA, or any regulatory authority for human or veterinary therapeutic use. It must not be administered to humans or animals. By purchasing, you confirm you are a qualified researcher and the material will be used only in a controlled laboratory setting.

What shipping options are available?

All orders ship from the USA via tracked courier within 24-48 hours of payment confirmation. Domestic delivery typically arrives within 2-5 business days in discreet, temperature-stable packaging. Tracking is provided by email at the time of dispatch.

How is SS-31 (Elamipretide) priced compared to other suppliers?

AscendLabz prices SS-31 (Elamipretide) competitively while maintaining ≥99% HPLC-verified purity and a full COA. Bulk-vial bundles offer additional savings for laboratories ordering multi-month research supply. Pricing is reviewed monthly to remain among the most affordable verified-purity sources in the United States.

What payment methods are accepted?

Cryptocurrency (Bitcoin, Ethereum, USDC, and others) is accepted with automatic discounts at checkout. Credit and debit cards are also supported through our secure payment processor. All transactions are encrypted end-to-end and order details are never shared with third parties.

Can I order SS-31 (Elamipretide) alongside other peptides?

Yes. Most laboratories order SS-31 (Elamipretide) together with complementary compounds from the mitochondrial-targeted research peptides category. Combined orders ship together with a single COA package and qualify for bulk-tier pricing. See the related compounds section below for commonly paired research peptides.

Related Research Compounds

Researchers ordering SS-31 (Elamipretide) frequently study it alongside these related compounds:

MOTS-c · NAD+ · Glutathione · 5-Amino-1MQ

Browse the complete catalog →

⚠️ Research Use Only
All products are strictly for laboratory research purposes only. Not for human consumption. SS-31 (Elamipretide) is not approved by the FDA for therapeutic use. For in vitro research and scientific study only.