Melanotan 1 (Afamelanotide)

Linear alpha-MSH analog — Potent melanocortin receptor agonist for melanogenesis, photoprotection, and skin pigmentation research

✓ 99%+ Purity HPLC Verified ✓ COA Included ✓ Fast USA Shipping ✓ alpha-MSH Analog ✓ Research Grade
From $49.99
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Melanotan 1 5mg Vial

Entry research supply — ideal for melanocortin receptor binding studies and initial melanogenesis protocols

$49.99
Order 5mg

Melanotan 1 10mg Vial

Extended supply — best value for longitudinal photoprotection and alpha-MSH receptor research

$89.99
Order 10mg

Melanotan 1 Research Pack (2×10mg)

Maximum supply for comprehensive MC1R research programs with multiple protocols

$129.99
Order 2-Pack

Why Researchers Choose AscendLabz

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99%+ Purity Guaranteed

Every Melanotan 1 batch is HPLC analyzed for sequence integrity and purity. Full COA with every order.

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Best USA Pricing

Premium afamelanotide from $49.99 — highest purity at competitive research pricing.

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Fast Discrete Shipping

Ships within 24–48 hours. Discreet packaging with tracked USA delivery on every order.

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Certificate of Analysis

Full COA with sequence verification, purity confirmation, and batch traceability included.

Melanotan 1 Specifications

Peptide NameMelanotan I / Afamelanotide (CUV1647)
TypeLinear alpha-MSH analog
Receptor TargetMC1R (Melanocortin-1 Receptor)
Molecular FormulaC₇₈H₁₁₁N₂₁O₁₉
Molecular Weight1646.85 g/mol
Purity≥99% (HPLC verified)
FormLyophilized powder
Storage-20°C (long-term), 2–8°C (short-term)
Available Sizes5mg, 10mg

Frequently Asked Questions

What is Melanotan 1 used for in research?

Melanotan 1 (Afamelanotide) is a linear alpha-MSH peptide studied for its activation of melanocortin receptors, particularly MC1R. Research focuses on melanogenesis (melanin production), photoprotection mechanisms, and pigmentation biology in dermatological and photobiology laboratory studies.

How does Melanotan 1 differ from Melanotan 2?

Melanotan 1 is a linear alpha-MSH analog with high MC1R selectivity, while Melanotan 2 is a cyclic analog with broader melanocortin receptor activity (MC1R, MC3R, MC4R, MC5R). MT-1 research focuses primarily on skin pigmentation and photoprotection, while MT-2 research also covers sexual function and appetite pathways.

Does AscendLabz provide a COA for Melanotan 1?

Yes — every Melanotan 1 order includes a Certificate of Analysis confirming ≥99% purity, sequence verification, and batch traceability for complete research documentation.

Research Background

Melanotan-1 is a synthetic analog of α-melanocyte-stimulating hormone (α-MSH) with selective MC1R activity studied as part of the melanocortin receptor agonist category. It is investigated in pre-clinical and in-vitro research models for its activity on MC1R-mediated melanogenesis pathways studied in vitro. The compound is supplied as a lyophilized powder of ≥99% HPLC-verified purity and is intended exclusively for laboratory research use under qualified scientific supervision.

AscendLabz Melanotan-1 is sourced from cGMP-aligned synthesis facilities and validated for identity, purity, and counter-ion content prior to release. Each lot is independently tested by HPLC, and a Certificate of Analysis (COA) detailing peak area, retention time, and batch number is provided with every order. This level of documentation is intended to support reproducible research and clear chain-of-custody record-keeping in academic and independent laboratory environments.

For research workflows, Melanotan-1 is most commonly characterized in cell-culture and isolated-tissue models where investigators examine selective MC1R agonism alongside complementary compounds in the α-MSH analog research peptides class. Reference standards and dose-response controls should be established by each laboratory prior to experimental use, and all material should be handled by trained personnel using appropriate personal protective equipment.

Storage, Handling & Reconstitution

Storage: Lyophilized Melanotan-1 is stable at -20°C protected from light. Reconstituted peptide should be refrigerated at 2-8°C and used within 30 days. Lyophilized peptides should be kept in original sealed packaging until use to prevent moisture uptake.

Reconstitution: Bring the lyophilized vial to room temperature before opening. Reconstitute with bacteriostatic water by injecting solvent down the inner wall of the vial; do not direct the stream onto the lyophilized cake. Gently swirl — do not vortex or shake — until fully dissolved. Allow 5-10 minutes for complete solvation.

Handling: Use sterile technique throughout. Wipe vial septa with isopropyl alcohol before each draw. Document reconstitution date, solvent volume, and resulting concentration on the vial label for traceability.

Extended Research FAQ

How is Melanotan-1 verified for purity?

Every batch of Melanotan-1 is analyzed by reverse-phase HPLC and confirmed to be ≥99% pure. Mass spectrometry confirms molecular identity, and counter-ion / residual-solvent panels are performed where applicable. The full Certificate of Analysis ships with each order and is also archived by lot number.

Is Melanotan-1 approved for human use?

No. Melanotan-1 is supplied strictly for in-vitro laboratory research and is not approved by the FDA, EMA, or any regulatory authority for human or veterinary therapeutic use. It must not be administered to humans or animals. By purchasing, you confirm you are a qualified researcher and the material will be used only in a controlled laboratory setting.

What shipping options are available?

All orders ship from the USA via tracked courier within 24-48 hours of payment confirmation. Domestic delivery typically arrives within 2-5 business days in discreet, temperature-stable packaging. Tracking is provided by email at the time of dispatch.

How is Melanotan-1 priced compared to other suppliers?

AscendLabz prices Melanotan-1 competitively while maintaining ≥99% HPLC-verified purity and a full COA. Bulk-vial bundles offer additional savings for laboratories ordering multi-month research supply. Pricing is reviewed monthly to remain among the most affordable verified-purity sources in the United States.

What payment methods are accepted?

Cryptocurrency (Bitcoin, Ethereum, USDC, and others) is accepted with automatic discounts at checkout. Credit and debit cards are also supported through our secure payment processor. All transactions are encrypted end-to-end and order details are never shared with third parties.

Can I order Melanotan-1 alongside other peptides?

Yes. Most laboratories order Melanotan-1 together with complementary compounds from the α-MSH analog research peptides category. Combined orders ship together with a single COA package and qualify for bulk-tier pricing. See the related compounds section below for commonly paired research peptides.

Related Research Compounds

Researchers ordering Melanotan-1 frequently study it alongside these related compounds:

Melanotan-2 · PT-141 · AHK-Cu · GHK-Cu

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⚠️ Research Use Only
All products are strictly for laboratory research purposes only. Not for human consumption. Melanotan 1 (Afamelanotide) is not approved by the FDA for therapeutic use in the United States. For in vitro research and scientific study only.