Growth Differentiation Factor 8 — TGF-beta superfamily protein for skeletal muscle regulation, body composition, and hypertrophy pathway research
Entry research supply — ideal for initial myostatin pathway and muscle atrophy signal studies
Extended supply for dose-response and muscle regulatory pathway research
Multi-vial kit for comprehensive body composition and TGF-beta signaling research
Every GDF-8 batch is analyzed for protein integrity and purity via HPLC. Full COA provided with every order.
High-quality myostatin research protein from $54.99 — premium quality at competitive rates.
Ships within 24–48 hours. Cold-chain packaging available. Tracked USA delivery on every order.
Full COA with protein identity confirmation, purity analysis, and batch traceability included.
| Protein Name | GDF-8 / Myostatin / Growth Differentiation Factor 8 |
| Protein Family | TGF-beta superfamily |
| Source | Recombinant (E. coli expression) |
| Molecular Weight | ~25 kDa (mature form, homodimer) |
| Purity | ≥99% (HPLC verified) |
| Endotoxin Level | <1.0 EU/mcg |
| Storage | -80°C (long-term), -20°C (short-term) |
| Available Sizes | 10mcg, 50mcg |
GDF-8, commonly known as myostatin, is a negative regulator of skeletal muscle mass. Research uses include studies of muscle atrophy signaling, body composition regulation, muscle hypertrophy pathways, and the development of myostatin inhibition strategies for muscle wasting conditions.
Myostatin acts as a brake on muscle development — it signals satellite cells to remain quiescent and limits muscle fiber hypertrophy. Laboratory research on GDF-8 explores how inhibiting or modulating this protein affects downstream muscle growth regulators including ActRIIB and Smad2/3 pathways.
Yes — every GDF-8 order includes a full Certificate of Analysis with protein identity, purity confirmation, and batch number for complete research documentation and traceability.
GDF-8 (Myostatin) is a recombinant growth differentiation factor 8, a TGF-β superfamily member regulating skeletal muscle mass studied as part of the tgf-β family / muscle research category. It is investigated in pre-clinical and in-vitro research models for its activity on ActRIIB receptor signaling, Smad2/3 phosphorylation, and muscle homeostasis pathways studied in vitro. The compound is supplied as a lyophilized powder of ≥99% HPLC-verified purity and is intended exclusively for laboratory research use under qualified scientific supervision.
AscendLabz GDF-8 (Myostatin) is sourced from cGMP-aligned synthesis facilities and validated for identity, purity, and counter-ion content prior to release. Each lot is independently tested by HPLC, and a Certificate of Analysis (COA) detailing peak area, retention time, and batch number is provided with every order. This level of documentation is intended to support reproducible research and clear chain-of-custody record-keeping in academic and independent laboratory environments.
For research workflows, GDF-8 (Myostatin) is most commonly characterized in cell-culture and isolated-tissue models where investigators examine ActRIIB receptor binding and Smad signaling alongside complementary compounds in the TGF-β superfamily research proteins class. Reference standards and dose-response controls should be established by each laboratory prior to experimental use, and all material should be handled by trained personnel using appropriate personal protective equipment.
Storage: Lyophilized GDF-8 is stable at -20°C in sealed amber vials. Reconstituted protein should be aliquoted, stored at -20°C, and used within 14 days. Avoid repeated freeze-thaw cycles. Lyophilized peptides should be kept in original sealed packaging until use to prevent moisture uptake.
Reconstitution: Bring the lyophilized vial to room temperature before opening. Reconstitute with sterile filtered acidified water by injecting solvent down the inner wall of the vial; do not direct the stream onto the lyophilized cake. Gently swirl — do not vortex or shake — until fully dissolved. Allow 5-10 minutes for complete solvation.
Handling: Use sterile technique throughout. Wipe vial septa with isopropyl alcohol before each draw. Document reconstitution date, solvent volume, and resulting concentration on the vial label for traceability.
Every batch of GDF-8 (Myostatin) is analyzed by reverse-phase HPLC and confirmed to be ≥99% pure. Mass spectrometry confirms molecular identity, and counter-ion / residual-solvent panels are performed where applicable. The full Certificate of Analysis ships with each order and is also archived by lot number.
No. GDF-8 (Myostatin) is supplied strictly for in-vitro laboratory research and is not approved by the FDA, EMA, or any regulatory authority for human or veterinary therapeutic use. It must not be administered to humans or animals. By purchasing, you confirm you are a qualified researcher and the material will be used only in a controlled laboratory setting.
All orders ship from the USA via tracked courier within 24-48 hours of payment confirmation. Domestic delivery typically arrives within 2-5 business days in discreet, temperature-stable packaging. Tracking is provided by email at the time of dispatch.
AscendLabz prices GDF-8 (Myostatin) competitively while maintaining ≥99% HPLC-verified purity and a full COA. Bulk-vial bundles offer additional savings for laboratories ordering multi-month research supply. Pricing is reviewed monthly to remain among the most affordable verified-purity sources in the United States.
Cryptocurrency (Bitcoin, Ethereum, USDC, and others) is accepted with automatic discounts at checkout. Credit and debit cards are also supported through our secure payment processor. All transactions are encrypted end-to-end and order details are never shared with third parties.
Yes. Most laboratories order GDF-8 (Myostatin) together with complementary compounds from the TGF-β superfamily research proteins category. Combined orders ship together with a single COA package and qualify for bulk-tier pricing. See the related compounds section below for commonly paired research peptides.
Researchers ordering GDF-8 (Myostatin) frequently study it alongside these related compounds:
ACE-031 · IGF-1 LR3 · Ipamorelin · Sermorelin
⚠️ Research Use Only
All products are strictly for laboratory research purposes only. Not for human consumption. GDF-8/Myostatin has not been approved by the FDA for therapeutic use. For in vitro research and scientific study only.